Saša M. Miladinović received his Ph.D. in analytical chemistry from the University of Arkansas (USA) under the supervision of Professor Charles L. Wilkins, working on high-resolution mass spectrometry of synthetic polymers. He then held postdoctoral fellowships at EPFL Lausanne in the laboratory of Professor Yury Tsybin, on high-resolution top-down mass spectrometry of intact proteins and peptides, and at ETH Zürich with Professor Ruedi Aebersold, on targeted and untargeted quantitative proteomics.
After several years in industry as a research scientist, developing quantitative LC-MS bioanalytical methods for small molecules, pharmaceuticals and proteins including monoclonal antibodies, he returned to academia. He is now Associate Professor of Bioanalytical Chemistry at HES-SO Valais/Wallis, where he leads the Mass Spectrometry and Separation Sciences Laboratory (MS³L).
He teaches mass spectrometry, separation science, structural elucidation, green analytical chemistry and proteomics at bachelor level, and bioanalysis in regulated environments and LC-MS proteomics for biomarker discovery at master level. He supervises bachelor each year.
Research: Mass Spectrometry and Separation Sciences Laboratory (MS³L)
MS³L develops and applies high-resolution quantitative mass spectrometry coupled to advanced separation techniques, addressing analytical challenges in biological, food, environmental and industrial samples. The group combines robust instrumentation with AI- and machine learning-based data processing; work currently supported by an Innosuisse grant.
Research topics:
- AI/ML-driven workflows for mass spectrometry data processing and method development
- Biopharmaceutical characterization and quantification
- Quantitative and qualitative proteomics and metabolomics
- Biomarker discovery
- Bioanalysis (e.g. antibiotics)
- Mycotoxin extraction and analysis in food
- Environmental contaminant screening (PFAS)
The group works across analytical chemistry and data science, develops scalable and reproducible methods, trains the next generation of analytical scientists, and collaborates with partners in academia, industry and the public sector.
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