Lorenza Garau Paganella's research lies at the intersection of cell biology, biomaterials, and mechanics, combining engineering and biological approaches to develop advanced in vitro models that recreate tissue-like environments for biomedical applications and diagnostics.
She studied Process Engineering at ETH Zurich, where she subsequently completed her PhD focusing on biomaterials, 3D skin models, and drug delivery. Her research background also includes experience at Roche, providing her with insights into industrial pharmaceutical research and development.
Following her PhD, she was awarded a grant from the Swiss National Science Foundation (SNSF) to pursue postdoctoral research at Stanford University. At Stanford, she established an independent research direction focused on engineering 3D in vitro cancer models, integrating biomaterials and cellular systems to investigate the tumor microenvironment and develop physiologically relevant platforms for cancer research.
Her expertise spans 3D cell culture, tissue engineering, hydrogel-based systems, cell-based biological assays, and the characterization of cellular responses to engineered microenvironments. Her research interests include cancer biology, cellular senescence, drug delivery, and the development of advanced experimental models for biomedical research and therapeutic evaluation.
Research interests and expertise:
- 3D cell culture, spheroids, and engineered tissue models
- Biomaterials, hydrogels, and tissue engineering
- Oncology and Cancer biology
- Aging and cellular senescence
- Cell-based biological assays and in vitro disease models
- Drug delivery and biomedical applications
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