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Knoops Adrien

Knoops Adrien

Adjoint-e scientifique HES B

Main skills

Molecular biology

Microbiology

Genomics

Bioinformatics

Microencapsulation

Recombinant peptides and proteins

Systems Biology

  • Contact

  • Research

  • Publications

  • Conferences

Main contract

Adjoint-e scientifique HES B

Desktop: ENP.19.N312

HES-SO Valais-Wallis - Haute Ecole d'Ingénierie
Rue de l'Industrie 23, 1950 Sion, CH
HEI - VS
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Ongoing

HTP phenotypic screening platform

Role: Collaborator

Requérant(e)s: Armin Baumschlager, Lonza AG

Financement: Innosuisse Swiss Innovation Agency

Description du projet:

The quantification of protein of interest (POI) is a major bottleneck in high throughput strain development for protein production. This project aims to solve this fundamental challenge. We propose a generally applicable method for the in vivo quantification without permanently modifying the POI.

Research team within HES-SO: Hanik Nils , Nyitrai Mark , Knoops Adrien

Partenaires professionnels: Armin Baumschlager, Lonza AG

Durée du projet: 01.11.2024 - 01.11.2027

State: Ongoing

2025

Sequencing of a Dairy Isolate Unlocks Kluyveromyces marxianus as a Host for Lactose Valorization
Scientific paper

Knoops Adrien

ACS Synthetic Biology, 2025 , vol.  14, no  7, pp.  2667-2680

Link to the publication

Competence shut-off by intracellular pheromone degradation in salivarius streptococci
Scientific paper

Knoops Adrien

PLoS Genetics, 2025 , vol.  18, no  5

Link to the publication

2024

Tri-Functional CRISPR Screen Reveals Overexpression of QDR2 and QDR3 Transporters Increase Fumaric Acid Production in Kluyveromyces marxianus
Scientific paper

Knoops Adrien

ACS Synthetic Biology, 2024 , vol.  14, no  12, pp.  4907-4922

Link to the publication

Uncovering the arsenal of class II bacteriocins in salivarius streptococci
Scientific paper

Knoops Adrien

Communications Biology, 2024 , vol.  7 (1), no  1511

Link to the publication

2022

Expanding natural transformation to improve beneficial lactic acid bacteria
Scientific paper

Knoops Adrien

FEMS Microbiolgy Reviews, 2022 , vol.  46, no  4

Link to the publication

A genome-wide CRISPR interference screen reveals an StkP-mediated connection between cell wall integrity and competence in Streptococcus salivarius
Scientific paper

Knoops Adrien

mSystems, 2022 , vol.  7 (6), no  e00735-22

Link to the publication

The CovRS environmental sensor directly controls the ComRS signaling system to orchestrate competence bimodality in Salivarius Streptococci
Scientific paper

Knoops Adrien

mBio, 2022 , no  e03125-21

Link to the publication

2019

Distinct and Specific Role of NlpC/P60 Endopeptidases LytA and LytB in Cell Elongation and Division of Lactobacillus plantarum
Scientific paper

Knoops Adrien

Frontiers in microbiology, 2019 , vol.  10, no  713

Link to the publication

2026

High-throughput screening of microbial libraries in semi-permeable capsules
Conference

Knoops Adrien

European Conference on Biotechnology, 28.06.2026 - 01.07.2026, Antwerpen - Belgium

Link to the conference

2020

The CovR environmental sensor orchestrates competence bimodality in commensal streptococci
Conference

Knoops Adrien

Griffith’s Legacy Symposium, 15.06.2020 - 15.06.2020, Virtual

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